Thymus

Parameters

Non-defeated mice

30 days of SDS mice

Vehicle

Ladasten, 30 mg/kg, i.p.

Vehicle

Ladasten, 30 mg/kg, i.p.

CD4⁺CD8⁻

6.8 ± 0.3

8.5 ± 0.6

9.5 ± 0.8^*

6.2 ± 0.4

CD4⁺CD8⁺

85.2 ± 1.9

75.2 ± 1.4

76.8 ± 2.6^*

83.2 ± 1.9

CD4⁻CD8⁺

2.4 ± 0.3

4.5 ± 0.5

4.4 ± 0.4^*

3.1 ± 0.2

Spleen

CD3⁺

33.9 ± 1.8

38.9 ± 1.8

21.6 ± 1.8^*

29.6 ± 1.3

CD4⁺CD8⁻

22.2 ± 1.6

25.1 ± 1.1

13.3 ± 1.5^*

19.5 ± 1.7

CD4⁻CD8⁺

11.5 ± 0.8

13.8 ± 0.9

7.9 ± 0.6^*

11.8 ± 0.9

Blood

CD3⁺

24.5 ± 1.2

23.8 ± 1.3

20.2 ± 1.7^*

24.5 ± 2.9

CD4⁺CD8⁻

14.4 ± 1.6

14.9 ± 0.9

11.5 ± 1.8 (р = 0.08)

15.2 ± 2.0

CD4⁻CD8⁺

10.1 ± 0.6

11.2 ± 1.1

9.5 ± 0.9

10.5 ± 1.8